The neurobiological pathophysiology of schizophrenia differs significantly between males and females, according to a new study. The findings suggest a possible need for more sex-specific treatments for schizophrenia. The study was the first to identify a number of sex-specific genes related to schizophrenia using neurons derived from induced pluripotent stem cells. The results were published in Nature Communications.
Co-ordinated by the University of Eastern Finland, the University of Helsinki and Karolinska Institutet, the study investigated the differences in gene and protein